indomethacin (indocid, indocin SR)
available over the counter: no
uses: mild to moderate pain and inflammation
caused by tendinitis, arthritis, bursitis, bout, soft tissue injury,
migraines, vascular headaches, menstrual cramps; because of it's
greater toxicity, should be used when other nonsteroidal antiinflammatory
medications are ineffective
mechanism of action: interferes with formation
of prostaglandins ( cause inflammation and make nerves more sensitive)
side effects
- common: nausea, vomiting, heartburn,
diarrhea, constipation, headache
- less common: ulcers or sores in mouth,
rashes or blistering of skin, ringing sound in ears, tingling of hands or
feet, seizures, blurred vision
- serious: shortness of breath, wheezing,
chest pain, peptic ulcer disease, kidney failure
concerns: inhibits blood coagulation, and may
increase bleeding at surgery; stop meds 3 days before surgery;
prolonged use may cause gastrointestinal problems |
